When taking isotretinoin, also known by its brand names like Accutane, it is crucial to be aware of certain precautions and things to avoid to ensure the medication's effectiveness and minimize potential side effects. Firstly, you should avoid the use of vitamin A supplements, as isotretinoin is a derivative of vitamin A, and excessive intake of this vitamin can lead to toxicity. Combining accutane for acne with vitamin A supplements may increase the risk of side effects.

Secondly, it is essential to avoid or limit alcohol consumption while on isotretinoin. Alcohol can exacerbate certain side effects of the medication, such as liver problems, and it may also reduce the drug's effectiveness in treating acne. Additionally, isotretinoin can cause dizziness or impair your ability to concentrate, so it's crucial to avoid activities like driving or operating heavy machinery if you experience these side effects. Overall, following your healthcare provider's guidance and being cautious about potential interactions or activities while taking isotretinoin is essential for a safe and effective treatment journey.