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May 24, 2022 · Xenazine (tetrabenazine) is a monoamine depletory used to treat Huntington's chorea (uncontrolled muscle movements) Xenazine reduces the amount of certain chemicals in the body that are overly active in people with Huntington's disease --- rxlist com xenazine-drug htmAug 23, 2023 · Tetrabenazine Generic name: Tetrabenazine (tet ra ben' a zeen) Brand name: Xenazine Dosage form: tablet (12 5mg, 25mg) Drug class: VMAT2 inhibitors Medically reviewed by Melisa Puckey, BPharm Last updated on Aug 23, 2023 Common side effects of the Tetrabenazine include: drowsiness, tiredness; depressed mood; nausea; or feeling anxious, agitated, or restless Serious side effects of the Tetrabenazine include: tremors, shaking, restless movement, problems with balance; uncontrolled muscle movements in the face (chewing, lip smacking, frowning, tongue movement Tetrabenazine is a white to slightly yellow crystalline powder that is sparingly soluble in water and soluble in ethanol Each XENAZINE (tetrabenazine) Tablet contains either 12 5 or 25 mg of tetrabenazine as the active ingredient Feb 2, 2022 · Tetrabenazine ( Xenazine ) is a medication used for a movement problem called chorea, which is a symptom of Huntington's disease It's available as a generic and is taken once or twice per day Tetrabenazine ( Xenazine ) has many risks and potential interactions with other medications Reviewed by: reference medscape com drug xenazine-tetrabenazine-343075--- medicalnewstoday com articles drugs-xenazineXenazine 12 5 mg tablet: lactose, magnesium stearate, maize starch, and talc Xenazine 25mg tablet: lactose, magnesium stearate, maize starch, talc, and yellow iron oxide as an inactive ingredient Storage Store at 25°C (77°F) excursions permitted to 15° to 30°C (59° to 86°F) Manufacturer Manufactured by: Recipharm Fontaine SASgo drugbank com drugs DB04844--- drugs com tetrabenazine html12 5 mg PO qDay initially; after 1 week, the dose should be increased to 12 5 mg q12hr Maintenance: Titrate slowly by weekly intervals of 12 5 mg day to identify dose that reduces chorea and is tolerated If daily dose is 37 5 to 50 mg day, administer in divided doses q8hr Not to exceed 25 mg per single dose for total daily dosage between 37 --- rxlist com tetrabenazine generic-drug htm--- drugs com availability generic-xenazine htmlXenazine is available in a generic form called tetrabenazine A generic drug is an exact copy of the active drug in a brand-name medication The generic is considered to be as safe and effective Mechanism of action Tetrabenazine is a reversible human vesicular monoamine transporter type 2 inhibitor (Ki = 100 nM) It acts within the basal ganglia and promotes depletion of monoamine neurotransmitters serotonin, norepinephrine, and dopamine from stores It also decreases uptake into synaptic vesicles --- webmd com drugs 2 drug-151569 xenazine-oral details--- drugs com xenazine html Generic drug availability, manufacturer information , and patent status on Xenazine --- goodrx com tetrabenazine what-isUsual Tetrabenazine Adult Dose for Huntington Disease: Initial dose: First week: 12 5 mg orally daily Second week: 12 5 mg orally 2 times daily Maintenance dose: Increase by 12 5 mg orally weekly to tolerated dose that reduces chorea Doses of 37 5mg to 50 mg daily should be administered in 3 divided doses Generic Name: tetrabenazine Tetrabenazine is used to decrease the uncontrollable movements (chorea) caused by Huntington's disease However, it is not a cure for the disease Tetrabenazine (Xenazine) is only approved for chorea from Huntington's disease, whereas Austedo (deutetrabenazine) is approved for chorea from Huntington's disease as well as tardive dyskinesia Tetrabenazine (Xenazine) is available as a lower-cost generic, but it also has more side effects compared to Austedo (deutetrabenazine) Finally Generic Xenazine Availability Last updated on Aug 7, 2024 Xenazine is a brand name of tetrabenazine, approved by the FDA in the following formulation(s): XENAZINE (tetrabenazine - tablet;oral) Manufacturer: BAUSCH Approval date: August 15, 2008 Strength(s): 12 5MG , 25MG ; Has a generic version of Xenazine been approved? Yes Xenazine 12 5 mg tablet Color: white Shape: round Imprint: CL 12 5 This medicine is a yellowish-buff, cylindrical, scored, tablet imprinted with "CL 25" Look up another drug Mar 17, 2023 · Generic version Xenazine is available in a generic form called tetrabenazine A generic drug is an exact copy of the active drug in a brand-name medication May 3, 2023 · Xenazine Generic name : tetrabenazine [ TET-ra-BEN-a-zeen ] Dosage form: tablet (12 5mg, 25mg) Drug class: VMAT2 inhibitors Medically reviewed by Melisa Puckey, BPharm Last updated on May 3, 2023 Uses
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